TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation

BACKGROUND: Tumour necrosis factor superfamily protein 14 (TNFSF14), also called LIGHT, is an important regulator of immunological and fibrosis diseases. However, its specific involvement in cardiac fibrosis and atrial fibrillation (AF) has not been fully elucidated. The objective of this study is t...

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Detalles Bibliográficos
Autores principales: Wu, Yirong, Zhan, Siyao, Chen, Lian, Sun, Mingrui, Li, Miaofu, Mou, Xuanting, Zhang, Zhen, Xu, Linhao, Xu, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424430/
https://www.ncbi.nlm.nih.gov/pubmed/37580750
http://dx.doi.org/10.1186/s12967-023-04381-3

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