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Long-Term Effects on Retinal Structure and Function in a Mouse Endothelin-1 Model of Retinal Ganglion Cell Degeneration

PURPOSE: To study the long-term effects of endothelin-1 (ET-1)–induced retinal pathologies in mouse, using clinically relevant tools. METHODS: Adult C57BL/6 mice (7–9 weeks old) were intravitreally injected with PBS (n = 10) or 0.25 (n = 8), 0.5 (n = 8), or 1 nmol ET-1 (n = 9) and examined using ele...

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Detalles Bibliográficos
Autores principales:	Lakshmanan, Yamunadevi, Wong, Francisca Siu Yin, Chan, Henry Ho-Lung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424801/ https://www.ncbi.nlm.nih.gov/pubmed/37561449 http://dx.doi.org/10.1167/iovs.64.11.15

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