The ubiquitin-like modifier FAT10 covalently modifies HUWE1 and strengthens the interaction of AMBRA1 and HUWE1

The ubiquitin-like modifier FAT10 is highly upregulated under inflammatory conditions and targets its conjugation substrates to the degradation by the 26S proteasome. This process termed FAT10ylation is mediated by an enzymatic cascade and includes the E1 activating enzyme ubiquitin-like modifier ac...

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Detalles Bibliográficos
Autores principales: Mueller, Stefanie, Bialas, Johanna, Ryu, Stella, Catone, Nicola, Aichem, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424871/
https://www.ncbi.nlm.nih.gov/pubmed/37578983
http://dx.doi.org/10.1371/journal.pone.0290002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424871/
https://www.ncbi.nlm.nih.gov/pubmed/37578983
http://dx.doi.org/10.1371/journal.pone.0290002

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