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#AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance

Antimicrobial resistance (AMR) continues to serve as a major global health crisis. Clinicians practising in this modern era are faced with ongoing challenges in the therapeutic management of patients suffering from antimicrobial-resistant infections. A strong educational understanding and synergisti...

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Autores principales: Liu, Elaine, Prinzi, Andrea M, Borjan, Jovan, Aitken, Samuel L, Bradford, Patricia A, Wright, William F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424884/
https://www.ncbi.nlm.nih.gov/pubmed/37583473
http://dx.doi.org/10.1093/jacamr/dlad097
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author Liu, Elaine
Prinzi, Andrea M
Borjan, Jovan
Aitken, Samuel L
Bradford, Patricia A
Wright, William F
author_facet Liu, Elaine
Prinzi, Andrea M
Borjan, Jovan
Aitken, Samuel L
Bradford, Patricia A
Wright, William F
author_sort Liu, Elaine
collection PubMed
description Antimicrobial resistance (AMR) continues to serve as a major global health crisis. Clinicians practising in this modern era are faced with ongoing challenges in the therapeutic management of patients suffering from antimicrobial-resistant infections. A strong educational understanding and synergistic application of clinical microbiology, infectious disease and pharmacological concepts can assist the adventuring clinician in the navigation of such cases. Important items include mobilizing laboratory testing for pathogen identification and susceptibility data, harnessing an understanding of intrinsic pathogen resistance, acknowledging epidemiological resistance trends, recognizing acquired AMR mechanisms, and consolidating these considerations when constructing an ideal pharmacological plan. In this article, we outline a novel framework by which to systematically approach clinical AMR, encourage AMR-related education and optimize therapeutic decision-making in AMR-related illnesses.
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spelling pubmed-104248842023-08-15 #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance Liu, Elaine Prinzi, Andrea M Borjan, Jovan Aitken, Samuel L Bradford, Patricia A Wright, William F JAC Antimicrob Resist Review Antimicrobial resistance (AMR) continues to serve as a major global health crisis. Clinicians practising in this modern era are faced with ongoing challenges in the therapeutic management of patients suffering from antimicrobial-resistant infections. A strong educational understanding and synergistic application of clinical microbiology, infectious disease and pharmacological concepts can assist the adventuring clinician in the navigation of such cases. Important items include mobilizing laboratory testing for pathogen identification and susceptibility data, harnessing an understanding of intrinsic pathogen resistance, acknowledging epidemiological resistance trends, recognizing acquired AMR mechanisms, and consolidating these considerations when constructing an ideal pharmacological plan. In this article, we outline a novel framework by which to systematically approach clinical AMR, encourage AMR-related education and optimize therapeutic decision-making in AMR-related illnesses. Oxford University Press 2023-08-14 /pmc/articles/PMC10424884/ /pubmed/37583473 http://dx.doi.org/10.1093/jacamr/dlad097 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Liu, Elaine
Prinzi, Andrea M
Borjan, Jovan
Aitken, Samuel L
Bradford, Patricia A
Wright, William F
#AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title_full #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title_fullStr #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title_full_unstemmed #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title_short #AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
title_sort #amrrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424884/
https://www.ncbi.nlm.nih.gov/pubmed/37583473
http://dx.doi.org/10.1093/jacamr/dlad097
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