Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland

Perineurioma is a relatively rare tumor with an occasionally difficult differential diagnosis. A 63-year-old woman underwent esophagogastroduodenoscopy, which revealed a 15 mm, slightly faded, flat, and elevated lesion in the gastric body. Biopsy revealed a bundle-like proliferation of spindle-shape...

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Autores principales: Yokosuka, Ryohsuke, Ikeya, Takashi, Yamato, Hiroshi, Kanomata, Naoki, Fukuda, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424895/
https://www.ncbi.nlm.nih.gov/pubmed/37583507
http://dx.doi.org/10.14309/crj.0000000000001110
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author Yokosuka, Ryohsuke
Ikeya, Takashi
Yamato, Hiroshi
Kanomata, Naoki
Fukuda, Katsuyuki
author_facet Yokosuka, Ryohsuke
Ikeya, Takashi
Yamato, Hiroshi
Kanomata, Naoki
Fukuda, Katsuyuki
author_sort Yokosuka, Ryohsuke
collection PubMed
description Perineurioma is a relatively rare tumor with an occasionally difficult differential diagnosis. A 63-year-old woman underwent esophagogastroduodenoscopy, which revealed a 15 mm, slightly faded, flat, and elevated lesion in the gastric body. Biopsy revealed a bundle-like proliferation of spindle-shaped cells; however, the diagnosis was unconfirmed. Endoscopic submucosal dissection was performed for diagnosis and treatment. Histopathological examination of the lesion revealed cell proliferation with short spindle-shaped and oval nuclei and little atypia in the lamina propria. Immunohistochemical examination indicated a perineurioma. Thus, when spindle-shaped cells are found on biopsy, it is necessary to consider the possibility of perineurioma.
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spelling pubmed-104248952023-08-15 Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland Yokosuka, Ryohsuke Ikeya, Takashi Yamato, Hiroshi Kanomata, Naoki Fukuda, Katsuyuki ACG Case Rep J Case Report Perineurioma is a relatively rare tumor with an occasionally difficult differential diagnosis. A 63-year-old woman underwent esophagogastroduodenoscopy, which revealed a 15 mm, slightly faded, flat, and elevated lesion in the gastric body. Biopsy revealed a bundle-like proliferation of spindle-shaped cells; however, the diagnosis was unconfirmed. Endoscopic submucosal dissection was performed for diagnosis and treatment. Histopathological examination of the lesion revealed cell proliferation with short spindle-shaped and oval nuclei and little atypia in the lamina propria. Immunohistochemical examination indicated a perineurioma. Thus, when spindle-shaped cells are found on biopsy, it is necessary to consider the possibility of perineurioma. Wolters Kluwer 2023-08-14 /pmc/articles/PMC10424895/ /pubmed/37583507 http://dx.doi.org/10.14309/crj.0000000000001110 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yokosuka, Ryohsuke
Ikeya, Takashi
Yamato, Hiroshi
Kanomata, Naoki
Fukuda, Katsuyuki
Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title_full Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title_fullStr Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title_full_unstemmed Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title_short Perineurioma Diagnosed After Endoscopic Treatment of Suspected Gastric Adenocarcinoma of the Fundic Gland
title_sort perineurioma diagnosed after endoscopic treatment of suspected gastric adenocarcinoma of the fundic gland
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424895/
https://www.ncbi.nlm.nih.gov/pubmed/37583507
http://dx.doi.org/10.14309/crj.0000000000001110
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