Cargando…

Rivaroxaban attenuates neutrophil maturation in the bone marrow niche

Pharmacological inhibition of factor Xa by rivaroxaban has been shown to mediate cardioprotection and is frequently used in patients with, e.g., atrial fibrillation. Rivaroxaban's anti-inflammatory actions are well known, but the underlying mechanisms are still incompletely understood. To date,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneckmann, R., Döring, M., Gerfer, S., Gorressen, S., Heitmeier, S., Helten, C., Polzin, A., Jung, C., Kelm, M., Fender, A. C., Flögel, U., Grandoch, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425524/ https://www.ncbi.nlm.nih.gov/pubmed/37580509 http://dx.doi.org/10.1007/s00395-023-01001-5

Ejemplares similares

Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus
por: Kohlmorgen, Christina, et al.
Publicado: (2021)

Multiparametric MRI identifies subtle adaptations for demarcation of disease transition in murine aortic valve stenosis
por: Quast, Christine, et al.
Publicado: (2022)

Depletion of circulating blood NOS3 increases severity of myocardial infarction and left ventricular dysfunction
por: Merx, Marc W., et al.
Publicado: (2013)

The effect of rivaroxaban on biomarkers in blood and plasma: a review of preclinical and clinical evidence
por: Schiffer, Sonja, et al.
Publicado: (2023)

Bone Marrow Lymphoid Niche Adaptation to Mature B Cell Neoplasms
por: Dumontet, Erwan, et al.
Publicado: (2021)

TAVR: nemesis of NOACs?
por: Polzin, Amin, et al.
Publicado: (2022)

Effects of Rivaroxaban on Platelet Activation and Platelet–Coagulation Pathway Interaction: In Vitro and In Vivo Studies
por: Perzborn, Elisabeth, et al.
Publicado: (2015)

Risks of Stroke and Mortality in Atrial Fibrillation Patients Treated With Rivaroxaban and Warfarin
por: Alberts, Mark, et al.
Publicado: (2020)

Cardiomyocyte p38 MAPKα suppresses a heart–adipose tissue–neutrophil crosstalk in heart failure development
por: Bottermann, Katharina, et al.
Publicado: (2022)

Elevated mean neutrophil volume represents altered neutrophil composition and reflects damage after myocardial infarction
por: van Hout, G. P. J., et al.
Publicado: (2015)

Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia
por: Wischmann, Patricia, et al.
Publicado: (2020)

Regional analysis of inflammation and contractile function in reperfused acute myocardial infarction by in vivo (19)F cardiovascular magnetic resonance in pigs
por: Bönner, Florian, et al.
Publicado: (2022)

Direct thrombin inhibitors, but not the direct factor Xa inhibitor rivaroxaban, increase tissue factor-induced hypercoagulability in vitro and in vivo
por: Perzborn, E, et al.
Publicado: (2014)

Use of Prestudy Heparin Did Not Influence the Efficacy and Safety of Rivaroxaban in Patients Treated for Symptomatic Venous Thromboem‐bolism in the EINSTEIN DVT and EINSTEIN PE Studies
por: Prandoni, Paolo, et al.
Publicado: (2015)

S1P Lyase Inhibition Starting After Ischemia/Reperfusion Improves Postischemic Cardiac Remodeling
por: Polzin, Amin, et al.
Publicado: (2022)

Immediate Discharge and Home Treatment With Rivaroxaban of Low‐risk Venous Thromboembolism Diagnosed in Two U.S. Emergency Departments: A One‐year Preplanned Analysis
por: Beam, Daren M., et al.
Publicado: (2015)

Comparison of Four Bleeding Risk Scores to Identify Rivaroxaban‐treated Patients With Venous Thromboembolism at Low Risk for Major Bleeding
por: Kline, Jeffrey A., et al.
Publicado: (2016)

The extravascular compartment of the bone marrow: a niche for Plasmodium falciparum gametocyte maturation?
por: Farfour, Eric, et al.
Publicado: (2012)

Treatment of Pulmonary Embolism With Rivaroxaban: Outcomes by Simplified Pulmonary Embolism Severity Index Score from a Post Hoc Analysis of the EINSTEIN PE Study
por: Fermann, Gregory J, et al.
Publicado: (2015)

Distinct Ecological Niche of Anal, Oral, and Cervical Mucosal Microbiomes in Adolescent Women
por: Smith, Benjamin C., et al.
Publicado: (2016)

Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1
por: Polzin, Amin, et al.
Publicado: (2022)

Impact of Bariatric Surgical Intervention on Peripheral Blood Neutrophil (PBN) Function in Obesity
por: Roberts, Helen M., et al.
Publicado: (2017)

Major adverse cardiac events and drug-coated balloon size in coronary interventions
por: Naguib, David, et al.
Publicado: (2018)

Noninvasive assessment of metabolic turnover during inflammation by in vivo deuterium magnetic resonance spectroscopy
por: Flocke, Vera, et al.
Publicado: (2023)

Physiological Maturation Lags Behind Behavioral Maturation in Newly Eclosed Drosophila melanogaster Males
por: Koppik, Mareike, et al.
Publicado: (2018)

4-hydroxytamoxifen does not deteriorate cardiac function in cardiomyocyte-specific MerCreMer transgenic mice
por: Heinen, Andre, et al.
Publicado: (2021)

Neutrophil extracellular traps and fibrocytes in ST-segment elevation myocardial infarction
por: Hofbauer, Thomas M., et al.
Publicado: (2019)

Neutrophil proteome shifts over the myocardial infarction time continuum
por: Daseke, Michael J., et al.
Publicado: (2019)

Effectiveness and Safety of Rivaroxaban 15 or 20 mg Versus Vitamin K Antagonists in Nonvalvular Atrial Fibrillation: A Population-Based New Users High-Dimensional Propensity Score Matched Cohorts Study
por: Blin, Patrick, et al.
Publicado: (2019)

Niche-modulated and niche-modulating genes in bone marrow cells
por: Cohen, Y, et al.
Publicado: (2012)

Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction
por: Reusswig, Friedrich, et al.
Publicado: (2022)

Neutrophil Maturity in Cancer
por: Mackey, John B. G., et al.
Publicado: (2019)

Persistence of Highly Pathogenic Avian Influenza H5N1 Virus Defined by Agro-Ecological Niche
por: Hogerwerf, Lenny, et al.
Publicado: (2010)

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils
por: Grassi, Luigi, et al.
Publicado: (2018)

Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery
por: Mastenbroek, T. G., et al.
Publicado: (2020)

Modulation of Bone and Marrow Niche by Cholesterol
por: Yin, Wenzhen, et al.
Publicado: (2019)

Regulation of the Bone Marrow Niche by Inflammation
por: Mitroulis, Ioannis, et al.
Publicado: (2020)

Bone marrow niches in myeloid neoplasms
por: Kitagawa, Masanobu, et al.
Publicado: (2019)

Bone marrow niches in myelodysplastic syndromes
por: Tosato, Giovanna, et al.
Publicado: (2021)

The Hematopoietic Bone Marrow Niche Ecosystem
por: Fröbel, Julia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pbgqkp9rfu1invpdic3u3e9euv