Downregulation of CLDN6 inhibits cell migration and invasion and promotes apoptosis by regulation of the JAK2/STAT3 signaling pathway in hepatocellular carcinoma

BACKGROUND: High expression of CLDN6 in hepatocellular carcinoma (HCC) has been widely reported. During this research, CLDN6’s effect on the infiltration, migration, and apoptosis of HCC cells was investigated. METHODS: Initially, the knockdown and overexpression of CLDN6 in HCC cells were carried o...

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Detalles Bibliográficos
Autores principales: He, Zhiyi, Fan, Fangtian, Xu, Zhidong, Zhang, Mei, Zhao, Rui, Ke, Xiquan, Wang, Qizhi, Yan, Shanjun, Zheng, Hailun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425638/
https://www.ncbi.nlm.nih.gov/pubmed/37588735
http://dx.doi.org/10.21037/tcr-23-19

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