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PORCN promotes hepatocellular carcinogenesis via Wnt/β-catenin-dependent manner

BACKGROUND: Porcupine O-acyltransferase (PORCN), a membrane-bound O-acyltransferase, is crucial in Wnt ligand palmitoylation. However, the roles of PORCN in the development of hepatocellular carcinoma (HCC) remain unknown. METHODS: Western blot, real-time quantitative polymerase chain reaction (RT-q...

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Detalles Bibliográficos
Autores principales: Wu, Shuzhen, Liu, Zhaoxiu, Chen, Jing, Ma, Tao, Wang, Liyang, Huang, Tianxin, Sheng, Yu, Huang, Wei, Lu, Cuihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425655/
https://www.ncbi.nlm.nih.gov/pubmed/37588740
http://dx.doi.org/10.21037/tcr-23-191