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PORCN promotes hepatocellular carcinogenesis via Wnt/β-catenin-dependent manner
BACKGROUND: Porcupine O-acyltransferase (PORCN), a membrane-bound O-acyltransferase, is crucial in Wnt ligand palmitoylation. However, the roles of PORCN in the development of hepatocellular carcinoma (HCC) remain unknown. METHODS: Western blot, real-time quantitative polymerase chain reaction (RT-q...
Autores principales: | Wu, Shuzhen, Liu, Zhaoxiu, Chen, Jing, Ma, Tao, Wang, Liyang, Huang, Tianxin, Sheng, Yu, Huang, Wei, Lu, Cuihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425655/ https://www.ncbi.nlm.nih.gov/pubmed/37588740 http://dx.doi.org/10.21037/tcr-23-191 |
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