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Chiral bifunctional organocatalysts for enantioselective synthesis of 3-substituted isoindolinones

A series of chiral bifunctional organocatalysts were prepared and used for enantioselective synthesis of 3-substituted isoindolinones from 2-formylarylnitriles and malonates through aldol-cyclization rearrangement tandem reaction in excellent yields and enantioselectivites (up to 87% yield and 95% e...

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Detalles Bibliográficos
Autores principales:	Hu, Xiao-Mu, Zhang, Rui, Dong, Hai, Jia, Yan-Yan, Bao, Guo-Qiang, Wang, Ping-An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425721/ https://www.ncbi.nlm.nih.gov/pubmed/37588978 http://dx.doi.org/10.1039/d3ra04350a

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