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Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial

PURPOSE: Cancer vaccines represent a novel treatment modality with a complementary mode of action addressing a crucial bottleneck for checkpoint inhibitor (CPI) efficacy. CPIs are expected to release brakes in T-cell responses elicited by vaccination, leading to more robust immune responses. Increas...

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Detalles Bibliográficos
Autores principales:	Ellingsen, Espen B., O'Day, Steven, Mezheyeuski, Artur, Gromadka, Agnieszka, Clancy, Trevor, Kristedja, Timothy S., Milhem, Mohammed, Zakharia, Yousef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Clinical Trials: Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425723/ https://www.ncbi.nlm.nih.gov/pubmed/37378632 http://dx.doi.org/10.1158/1078-0432.CCR-23-0416

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