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IRE1α regulates the PTHrP-IHH feedback loop to orchestrate chondrocyte hypertrophy and cartilage mineralization

Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes, in which the Indian hedgehog (IHH) and parathyroid hormone-related protein-parathyroid hormone-1 receptor (PTHrP-PTH1R) feedback loop is crucial. The inositol-requiring enzym...

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Detalles Bibliográficos
Autores principales: Fan, Mengtian, Geng, Nana, Li, Xingyue, Yin, Danyang, Yang, Yuyou, Jiang, Rong, Chen, Cheng, Feng, Naibo, Liang, Li, Li, Xiaoli, Luo, Fengtao, Qi, Huabing, Tan, Qiaoyan, Xie, Yangli, Guo, Fengjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425753/
https://www.ncbi.nlm.nih.gov/pubmed/37588212
http://dx.doi.org/10.1016/j.gendis.2022.11.021