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IRE1α regulates the PTHrP-IHH feedback loop to orchestrate chondrocyte hypertrophy and cartilage mineralization
Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes, in which the Indian hedgehog (IHH) and parathyroid hormone-related protein-parathyroid hormone-1 receptor (PTHrP-PTH1R) feedback loop is crucial. The inositol-requiring enzym...
Autores principales: | Fan, Mengtian, Geng, Nana, Li, Xingyue, Yin, Danyang, Yang, Yuyou, Jiang, Rong, Chen, Cheng, Feng, Naibo, Liang, Li, Li, Xiaoli, Luo, Fengtao, Qi, Huabing, Tan, Qiaoyan, Xie, Yangli, Guo, Fengjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425753/ https://www.ncbi.nlm.nih.gov/pubmed/37588212 http://dx.doi.org/10.1016/j.gendis.2022.11.021 |
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