IL-13/IL-13RA2 signaling promotes colorectal cancer stem cell tumorigenesis by inducing ubiquitinated degradation of p53

Cancer stem cells (CSCs) are considered tumor-initiating cells and the main drivers of disease progression. Targeting these rare cancer cells, however, remains challenging with respect to therapeutic benefit. Here, we report the up-regulation of IL-13RA2 expression in colorectal cancer (CRC) tissues...

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Detalles Bibliográficos
Autores principales: He, Baoyu, Liang, Jing, Qin, Qianqian, Zhang, Yuqin, Shi, Shuo, Cao, Jinghe, Zhang, Zhixin, Bie, Qingli, Zhao, Rou, Wei, Li, Zhang, Baogui, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425805/
https://www.ncbi.nlm.nih.gov/pubmed/37588218
http://dx.doi.org/10.1016/j.gendis.2023.01.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425805/
https://www.ncbi.nlm.nih.gov/pubmed/37588218
http://dx.doi.org/10.1016/j.gendis.2023.01.027

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