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Characterization of the REC114‐MEI4‐IHO1 complex regulating meiotic DNA double‐strand break formation

Meiotic recombination is initiated by the formation of DNA double‐strand breaks (DSBs), essential for fertility and genetic diversity. In the mouse, DSBs are formed by the catalytic TOPOVIL complex consisting of SPO11 and TOPOVIBL. To preserve genome integrity, the activity of the TOPOVIL complex is...

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Detalles Bibliográficos
Autores principales:	Laroussi, Hamida, Juarez‐Martinez, Ariadna B, Le Roy, Aline, Boeri Erba, Elisabetta, Gabel, Frank, de Massy, Bernard, Kadlec, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425845/ https://www.ncbi.nlm.nih.gov/pubmed/37431931 http://dx.doi.org/10.15252/embj.2023113866

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