Phenotypic features of dystrophin gene knockout pigs harboring a human artificial chromosome containing the entire dystrophin gene

Mammalian artificial chromosomes have enabled the introduction of extremely large amounts of genetic information into animal cells in an autonomously replicating, nonintegrating format. However, the evaluation of human artificial chromosomes (HACs) as novel tools for curing intractable hereditary di...

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Detalles Bibliográficos
Autores principales: Watanabe, Masahito, Miyamoto, Hitomaru, Okamoto, Kazutoshi, Nakano, Kazuaki, Matsunari, Hitomi, Kazuki, Kanako, Hasegawa, Koki, Uchikura, Ayuko, Takayanagi, Shuko, Umeyama, Kazuhiro, Hiramuki, Yosuke, Kemter, Elisabeth, Klymuik, Nikolai, Kurome, Mayuko, Kessler, Barbara, Wolf, Eckhard, Kazuki, Yasuhiro, Nagashima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425850/
https://www.ncbi.nlm.nih.gov/pubmed/37588685
http://dx.doi.org/10.1016/j.omtn.2023.07.021

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