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IPX203 vs Immediate-Release Carbidopa-Levodopa for the Treatment of Motor Fluctuations in Parkinson Disease: The RISE-PD Randomized Clinical Trial
IMPORTANCE: Levodopa has a short half-life and a limited window of opportunity for absorption in the proximal small intestine. IPX203 is an oral, extended-release formulation of carbidopa-levodopa developed to address these limitations. OBJECTIVE: To assess the efficacy and safety of IPX203 vs immed...
Autores principales: | Hauser, Robert A., Espay, Alberto J., Ellenbogen, Aaron L., Fernandez, Hubert H., Isaacson, Stuart H., LeWitt, Peter A., Ondo, William G., Pahwa, Rajesh, Schwarz, Johannes, Stocchi, Fabrizio, Zeitlin, Leonid, Banisadr, Ghazal, Fisher, Stanley, Visser, Hester, D’Souza, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425876/ https://www.ncbi.nlm.nih.gov/pubmed/37578800 http://dx.doi.org/10.1001/jamaneurol.2023.2679 |
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