Cargando…

Epigenetic instability caused by absence of CIZ1 drives transformation during quiescence cycles

BACKGROUND: Cip1-interacting zinc finger protein 1 (CIZ1) forms RNA-dependent protein assemblies that stabilise epigenetic state, notable at the inactive X chromosome in females. CIZ1 has been linked with a range of human cancers and in mice genetic deletion of CIZ1 manifests as hyperproliferative l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dobbs, Olivia G., Wilson, Rosemary H. C., Newling, Katherine, Ainscough, Justin F.-X., Coverley, Dawn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426085/ https://www.ncbi.nlm.nih.gov/pubmed/37580709 http://dx.doi.org/10.1186/s12915-023-01671-6

Ejemplares similares

Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term culture
por: Stewart, Emma R., et al.
Publicado: (2019)

Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome
por: Sofi, Sajad, et al.
Publicado: (2022)

A quantitative immunoassay for lung cancer biomarker CIZ1b in patient plasma
por: Coverley, Dawn, et al.
Publicado: (2017)

Cardiomyocyte-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart
por: Bageghni, Sumia A., et al.
Publicado: (2016)

CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours
por: Swarts, Dorian R.A., et al.
Publicado: (2018)

Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1
por: Thacker, Urvi, et al.
Publicado: (2020)

The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory
por: Ridings-Figueroa, Rebeca, et al.
Publicado: (2017)

Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray
por: Rahman, Faisal A, et al.
Publicado: (2010)

Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis
por: Pauzaite, Tekle, et al.
Publicado: (2016)

Transformation-induced changes in the DNA-nuclear matrix interface, revealed by high-throughput analysis of DNA halos
por: Wilson, Rosemary H. C., et al.
Publicado: (2017)

From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle
por: Gérard, Claude, et al.
Publicado: (2012)

Relationship between DNA replication and the nuclear matrix
por: Wilson, Rosemary H C, et al.
Publicado: (2013)

Polarized Growth in the Absence of F-Actin in Saccharomyces cerevisiae Exiting Quiescence
por: Sahin, Annelise, et al.
Publicado: (2008)

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium
por: Schlereth, Katharina, et al.
Publicado: (2018)

The Role of Cdkn1A-Interacting Zinc Finger Protein 1 (CIZ1) in DNA Replication and Pathophysiology
por: Liu, Qiang, et al.
Publicado: (2016)

The conserved HDAC Rpd3 drives transcriptional quiescence in S. cerevisiae
por: McKnight, Jeffrey N., et al.
Publicado: (2015)

CycleFlow simultaneously quantifies cell-cycle phase lengths and quiescence in vivo
por: Jolly, Adrien, et al.
Publicado: (2022)

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells
por: Munkley, Jennifer, et al.
Publicado: (2011)

The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein–induced bone formation
por: Morinobu, Mikihiko, et al.
Publicado: (2005)

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence
por: Griger, Joscha, et al.
Publicado: (2017)

The regenerating skeletal muscle niche drives satellite cell return to quiescence
por: Cutler, Alicia A., et al.
Publicado: (2022)

Elevated Levels of Mislocalised, Constitutive Ras Signalling Can Drive Quiescence by Uncoupling Cell-Cycle Regulation from Metabolic Homeostasis
por: Piper-Brown, Elliot, et al.
Publicado: (2023)

Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth
por: Sun, Gongping, et al.
Publicado: (2020)

CIZ1 aggravates gastric cancer progression via mediating FBXL19-AS1 and miR-339-3p
por: Wan, Houmin, et al.
Publicado: (2023)

Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates
por: Pelletier, Alexandre, et al.
Publicado: (2022)

Micro‐Topographies Induce Epigenetic Reprogramming and Quiescence in Human Mesenchymal Stem Cells
por: Vermeulen, Steven, et al.
Publicado: (2022)

Quantum Fourier transform to estimate drive cycles
por: Dixit, Vinayak, et al.
Publicado: (2022)

Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas
por: Takeuchi, Tomomi, et al.
Publicado: (2019)

Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence
por: Matson, Jacob Peter, et al.
Publicado: (2019)

The emerging role of cancer cell plasticity and cell-cycle quiescence in immune escape
por: Bruschini, Sara, et al.
Publicado: (2020)

Monitoring single-cell dynamics of entry into quiescence during an unperturbed life cycle
por: Jacquel, Basile, et al.
Publicado: (2021)

Cell cycle exits and U-turns: Quiescence as multiple reversible forms of arrest
por: Johnson, Martha Sharisha, et al.
Publicado: (2023)

(R)-2-hydroxyglutarate drives immune quiescence in the tumor microenvironment of IDH-mutant gliomas
por: Richardson, Leland G., et al.
Publicado: (2019)

Epigenetic memory of drug exposure history controls neural stem cell quiescence in the adult brain
por: Iwamoto, Masakazu, et al.
Publicado: (2023)

Monitoring Spontaneous Quiescence and Asynchronous Proliferation-Quiescence Decisions in Prostate Cancer Cells
por: Pulianmackal, Ajai J., et al.
Publicado: (2021)

Metabolic status rather than cell cycle signals control quiescence entry and exit
por: Laporte, Damien, et al.
Publicado: (2011)

A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit
por: Laporte, Damien, et al.
Publicado: (2015)

Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence
por: Ferreira, Silvia A., et al.
Publicado: (2018)

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
por: Grant, Francis M., et al.
Publicado: (2020)

Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation
por: Li, Zhentian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q0dvslf37755f2f5g5ok6dhfet