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Evolutionary analysis of the mTOR pathway provide insights into lifespan extension across mammals
BACKGROUND: Lifespan extension has independently evolved several times during mammalian evolution, leading to the emergence of a group of long-lived animals. Though mammalian/mechanistic target of rapamycin (mTOR) signaling pathway is shown as a central regulator of lifespan and aging, the underlyin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426088/ https://www.ncbi.nlm.nih.gov/pubmed/37582720 http://dx.doi.org/10.1186/s12864-023-09554-4 |