Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors

BACKGROUND: New therapies are urgently needed in melanoma, particularly in late-stage patients not responsive to immunotherapies and kinase inhibitors. To uncover novel potentiators of T cell anti-tumor immunity, we carried out an ex vivo pharmacological screen and identified 5-Nonyloxytryptamine (5...

Descripción completa

Detalles Bibliográficos
Autores principales: Stachura, Paweł, Liu, Wei, Xu, Haifeng C., Wlodarczyk, Agnès, Stencel, Olivia, Pandey, Piyush, Vogt, Melina, Bhatia, Sanil, Picard, Daniel, Remke, Marc, Lang, Karl S., Häussinger, Dieter, Homey, Bernhard, Lang, Philipp A., Borkhardt, Arndt, Pandyra, Aleksandra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426104/
https://www.ncbi.nlm.nih.gov/pubmed/37582744
http://dx.doi.org/10.1186/s12943-023-01833-8

Ejemplares similares

Ejemplares similares