Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer’s disease

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BACKGROUND: Age is the strongest risk factor for the development of Alzheimer’s disease (AD). Besides the pathological hallmarks of β-amyloid (Aβ) plaques and neurofibrillary tangles, emerging evidence demonstrates a critical role of microglia and neuroinflammation in AD pathogenesis. Oleoylethanola...

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Detalles Bibliográficos
Autores principales: Comerota, Michele M., Gedam, Manasee, Xiong, Wen, Jin, Feng, Deng, Lisheng, Wang, Meng C., Wang, Jin, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426131/
https://www.ncbi.nlm.nih.gov/pubmed/37580742
http://dx.doi.org/10.1186/s13024-023-00648-x
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