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Transferrin-Conjugated PLGA Nanoparticles for Co-Delivery of Temozolomide and Bortezomib to Glioblastoma Cells

[Image: see text] Glioblastoma (GBM) represents almost half of primary brain tumors, and its standard treatment with the alkylating agent temozolomide (TMZ) is not curative. Treatment failure is partially related to intrinsic resistance mechanisms mediated by the O6-methylguanine-DNA methyltransfera...

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Detalles Bibliográficos
Autores principales: Ramalho, Maria João, Torres, Inês David, Loureiro, Joana Angélica, Lima, Jorge, Pereira, Maria Carmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426337/
https://www.ncbi.nlm.nih.gov/pubmed/37588263
http://dx.doi.org/10.1021/acsanm.3c02122

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