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Receptor-mediated drug delivery of bispecific therapeutic antibodies through the blood-brain barrier
Therapeutic antibody drug development is a rapidly growing sector of the pharmaceutical industry. However, antibody drug development for the brain is a technical challenge, and therapeutic antibodies for the central nervous system account for ~3% of all such agents. The principal obstacle to antibod...
Autor principal: | Pardridge, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426772/ https://www.ncbi.nlm.nih.gov/pubmed/37583474 http://dx.doi.org/10.3389/fddev.2023.1227816 |
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