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Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease

OBJECTIVE: Inflammatory bowel diseases may have extra intestinal manifestations such as those affecting the skin. This study aimed to study skin manifestations in a cohort of Brazilian patients with inflammatory bowel diseases. METHODS: Epidemiological and clinical data were obtained through a cross...

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Autores principales: da Silveira, Taciana Malosti, Kroyzanovski, Milena, Purim, Katia Sheylla Malta, Ramos, Odery, Skare, Thelma, Nisihara, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Médica Brasileira 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427176/
https://www.ncbi.nlm.nih.gov/pubmed/37585986
http://dx.doi.org/10.1590/1806-9282.20230165
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author da Silveira, Taciana Malosti
Kroyzanovski, Milena
Purim, Katia Sheylla Malta
Ramos, Odery
Skare, Thelma
Nisihara, Renato
author_facet da Silveira, Taciana Malosti
Kroyzanovski, Milena
Purim, Katia Sheylla Malta
Ramos, Odery
Skare, Thelma
Nisihara, Renato
author_sort da Silveira, Taciana Malosti
collection PubMed
description OBJECTIVE: Inflammatory bowel diseases may have extra intestinal manifestations such as those affecting the skin. This study aimed to study skin manifestations in a cohort of Brazilian patients with inflammatory bowel diseases. METHODS: Epidemiological and clinical data were obtained through a cross-sectional study of 70 inflammatory bowel diseases patients and a control group comprising 50 healthy individuals. All patients were subjected to dermatological examination and photography of skin lesions. RESULTS: Out of the 70 inflammatory bowel diseases patients, 50 had ulcerative colitis and 20 had Crohn’s disease. Skin lesions occurred in 95.7% of the inflammatory bowel diseases patients and in 88% of individuals in the control group (p=0.001). Alopecia (p<0.0001), xerosis (p=0.03), striae (p=0.02), and acne (p=0.04) were more common in inflammatory bowel diseases patients than in the control group. Alopecia was more frequent in females (p=0.01) than in males. Two male patients, one with ulcerative colitis and the other with Crohn’s disease, had pyoderma gangrenosum. Erythema nodosum was not observed in both groups. CONCLUSION: There was a high prevalence of skin lesions in the Brazilian inflammatory bowel diseases patients. Additionally, alopecia, xerosis, striae, and acne were more common in patients with inflammatory bowel diseases than in those in the control group.
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spelling pubmed-104271762023-08-16 Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease da Silveira, Taciana Malosti Kroyzanovski, Milena Purim, Katia Sheylla Malta Ramos, Odery Skare, Thelma Nisihara, Renato Rev Assoc Med Bras (1992) Original Article OBJECTIVE: Inflammatory bowel diseases may have extra intestinal manifestations such as those affecting the skin. This study aimed to study skin manifestations in a cohort of Brazilian patients with inflammatory bowel diseases. METHODS: Epidemiological and clinical data were obtained through a cross-sectional study of 70 inflammatory bowel diseases patients and a control group comprising 50 healthy individuals. All patients were subjected to dermatological examination and photography of skin lesions. RESULTS: Out of the 70 inflammatory bowel diseases patients, 50 had ulcerative colitis and 20 had Crohn’s disease. Skin lesions occurred in 95.7% of the inflammatory bowel diseases patients and in 88% of individuals in the control group (p=0.001). Alopecia (p<0.0001), xerosis (p=0.03), striae (p=0.02), and acne (p=0.04) were more common in inflammatory bowel diseases patients than in the control group. Alopecia was more frequent in females (p=0.01) than in males. Two male patients, one with ulcerative colitis and the other with Crohn’s disease, had pyoderma gangrenosum. Erythema nodosum was not observed in both groups. CONCLUSION: There was a high prevalence of skin lesions in the Brazilian inflammatory bowel diseases patients. Additionally, alopecia, xerosis, striae, and acne were more common in patients with inflammatory bowel diseases than in those in the control group. Associação Médica Brasileira 2023-08-14 /pmc/articles/PMC10427176/ /pubmed/37585986 http://dx.doi.org/10.1590/1806-9282.20230165 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
da Silveira, Taciana Malosti
Kroyzanovski, Milena
Purim, Katia Sheylla Malta
Ramos, Odery
Skare, Thelma
Nisihara, Renato
Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title_full Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title_fullStr Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title_full_unstemmed Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title_short Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
title_sort prevalence of skin lesions in a sample of brazilian patients with inflammatory bowel disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427176/
https://www.ncbi.nlm.nih.gov/pubmed/37585986
http://dx.doi.org/10.1590/1806-9282.20230165
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