Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement

Cell migration through confining three dimensional (3D) topographies can lead to loss of nuclear envelope integrity, DNA damage, and genomic instability. Despite these detrimental phenomena, cells transiently exposed to confinement do not usually die. Whether this is also true for cells subjected to...

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Detalles Bibliográficos
Autores principales: Hemmati, Farnaz, Akinpelu, Ayuba, Song, Jiyeon, Amiri, Farshad, McDaniel, Anya, McMurray, Collins, Afthinos, Alexandros, Andreadis, Stelios T., Aitken, Andrew V., Biancardi, Vinicia C., Gerecht, Sharon, Mistriotis, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427377/
https://www.ncbi.nlm.nih.gov/pubmed/37267923
http://dx.doi.org/10.1002/advs.202302228

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