Fast kernel-based association testing of non-linear genetic effects for biobank-scale data

Our knowledge of non-linear genetic effects on complex traits remains limited, in part, due to the modest power to detect such effects. While kernel-based tests offer a versatile approach to test for non-linear relationships between sets of genetic variants and traits, current approaches cannot be a...

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Detalles Bibliográficos
Autores principales: Fu, Boyang, Pazokitoroudi, Ali, Sudarshan, Mukund, Liu, Zhengtong, Subramanian, Lakshminarayanan, Sankararaman, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427662/
https://www.ncbi.nlm.nih.gov/pubmed/37582955
http://dx.doi.org/10.1038/s41467-023-40346-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427662/
https://www.ncbi.nlm.nih.gov/pubmed/37582955
http://dx.doi.org/10.1038/s41467-023-40346-2

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