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Fast kernel-based association testing of non-linear genetic effects for biobank-scale data
Our knowledge of non-linear genetic effects on complex traits remains limited, in part, due to the modest power to detect such effects. While kernel-based tests offer a versatile approach to test for non-linear relationships between sets of genetic variants and traits, current approaches cannot be a...
Autores principales: | Fu, Boyang, Pazokitoroudi, Ali, Sudarshan, Mukund, Liu, Zhengtong, Subramanian, Lakshminarayanan, Sankararaman, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427662/ https://www.ncbi.nlm.nih.gov/pubmed/37582955 http://dx.doi.org/10.1038/s41467-023-40346-2 |
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