Sexual dimorphism in the social behaviour of Cntnap2-null mice correlates with disrupted synaptic connectivity and increased microglial activity in the anterior cingulate cortex

A biological understanding of the apparent sex bias in autism is lacking. Here we have identified Cntnap2 KO mice as a model system to help better understand this dimorphism. Using this model, we observed social deficits in juvenile male KO mice only. These male-specific social deficits correlated w...

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Detalles Bibliográficos
Autores principales: Dawson, Matt S., Gordon-Fleet, Kevin, Yan, Lingxin, Tardos, Vera, He, Huanying, Mui, Kwong, Nawani, Smriti, Asgarian, Zeinab, Catani, Marco, Fernandes, Cathy, Drescher, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427688/
https://www.ncbi.nlm.nih.gov/pubmed/37582968
http://dx.doi.org/10.1038/s42003-023-05215-0

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