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Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)

Mercury ions (Hg(2+)) are widely found in the environment; it is considered a major pollutant. Therefore, the rapid and reliable detection of Hg(2+) is of great technical interest. In this study, a highly fluorescent, sensitive, and selective fluorometric assay for detecting Hg(2+) ions was develope...

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Autores principales: Tiwari, Atul Kumar, Yadav, Hari Prakash, Gupta, Munesh Kumar, Narayan, Roger J., Pandey, Prem C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427866/
https://www.ncbi.nlm.nih.gov/pubmed/37593107
http://dx.doi.org/10.3389/fchem.2023.1238631
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author Tiwari, Atul Kumar
Yadav, Hari Prakash
Gupta, Munesh Kumar
Narayan, Roger J.
Pandey, Prem C.
author_facet Tiwari, Atul Kumar
Yadav, Hari Prakash
Gupta, Munesh Kumar
Narayan, Roger J.
Pandey, Prem C.
author_sort Tiwari, Atul Kumar
collection PubMed
description Mercury ions (Hg(2+)) are widely found in the environment; it is considered a major pollutant. Therefore, the rapid and reliable detection of Hg(2+) is of great technical interest. In this study, a highly fluorescent, sensitive, and selective fluorometric assay for detecting Hg(2+) ions was developed using vancomycin functionalized and polyethyleneimine stabilized gold nanoparticles (PEI-f-AuNPs@Van). The as-made gold nanoparticles were highly fluorescent, with excitation and emission maxima occurring at 320 and 418 nm, respectively. The size of nanoparticles was ~7 nm; a zeta potential of ~38.8 mV was determined. The XRD analysis confirmed that the nanoparticles possessed crystalline structure with face centerd cubic symmetry. Using the PEI-f-AuNP@Van probe, the detection limit of Hg(2+) ion was achieved up to 0.988 nM (within a linear range) by calculating the KSV. However, the detection limit in a natural environmental sample was shown to be 12.5 nM. Furthermore, the selectivity tests confirmed that the designed probe was highly selective to mercury (II) cations among tested other divalent cations. Owing to its sensitivity and selectivity, this approach for Hg(2+) ions detection can be utilized for the analysis of real water samples.
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spelling pubmed-104278662023-08-17 Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II) Tiwari, Atul Kumar Yadav, Hari Prakash Gupta, Munesh Kumar Narayan, Roger J. Pandey, Prem C. Front Chem Chemistry Mercury ions (Hg(2+)) are widely found in the environment; it is considered a major pollutant. Therefore, the rapid and reliable detection of Hg(2+) is of great technical interest. In this study, a highly fluorescent, sensitive, and selective fluorometric assay for detecting Hg(2+) ions was developed using vancomycin functionalized and polyethyleneimine stabilized gold nanoparticles (PEI-f-AuNPs@Van). The as-made gold nanoparticles were highly fluorescent, with excitation and emission maxima occurring at 320 and 418 nm, respectively. The size of nanoparticles was ~7 nm; a zeta potential of ~38.8 mV was determined. The XRD analysis confirmed that the nanoparticles possessed crystalline structure with face centerd cubic symmetry. Using the PEI-f-AuNP@Van probe, the detection limit of Hg(2+) ion was achieved up to 0.988 nM (within a linear range) by calculating the KSV. However, the detection limit in a natural environmental sample was shown to be 12.5 nM. Furthermore, the selectivity tests confirmed that the designed probe was highly selective to mercury (II) cations among tested other divalent cations. Owing to its sensitivity and selectivity, this approach for Hg(2+) ions detection can be utilized for the analysis of real water samples. Frontiers Media S.A. 2023-08-01 /pmc/articles/PMC10427866/ /pubmed/37593107 http://dx.doi.org/10.3389/fchem.2023.1238631 Text en Copyright © 2023 Tiwari, Yadav, Gupta, Narayan and Pandey. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Tiwari, Atul Kumar
Yadav, Hari Prakash
Gupta, Munesh Kumar
Narayan, Roger J.
Pandey, Prem C.
Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title_full Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title_fullStr Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title_full_unstemmed Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title_short Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)
title_sort synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (ii)
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427866/
https://www.ncbi.nlm.nih.gov/pubmed/37593107
http://dx.doi.org/10.3389/fchem.2023.1238631
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