Cargando…

Identifying a Lung Stem Cell Subpopulation by Combining Single-Cell Morphometrics, Organoid Culture, and Transcriptomics

Single-cell RNA sequencing is a valuable tool for dissecting cellular heterogeneity in complex systems. However, it is still challenging to estimate the proliferation and differentiation potentials of subpopulations within dormant tissue stem cells. Here, we established a new single-cell analysis me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujimura, Takashi, Enomoto, Yasunori, Katsura, Hiroaki, Ogawa, Taisaku, Baba, Saori, Ogata, Akira, Yamaoka, Akira, Shiroguchi, Katsuyuki, Morimoto, Mitsuru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427966/ https://www.ncbi.nlm.nih.gov/pubmed/37468433 http://dx.doi.org/10.1093/stmcls/sxad044

Ejemplares similares

Constitutive activity of a G protein‐coupled receptor, DRD1, contributes to human cerebral organoid formation
por: Wang, Qinying, et al.
Publicado: (2020)

Combined Characterization of microRNA and mRNA Profiles Delineates Early Differentiation Pathways of CD133(+) and CD34(+) Hematopoietic Stem and Progenitor Cells
por: Bissels, Ute, et al.
Publicado: (2011)

Concise Review: Bone Marrow-Derived Stem/Progenitor Cells in Cutaneous Repair and Regeneration
por: Wu, Yaojiong, et al.
Publicado: (2010)

Histone Deacetylase Inhibition with Valproic Acid Downregulates Osteocalcin Gene Expression in Human Dental Pulp Stem Cells and Osteoblasts: Evidence for HDAC2 Involvement
por: Paino, Francesca, et al.
Publicado: (2014)

Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p
por: Barter, Matt J., et al.
Publicado: (2015)

The epitranscriptome landscape of small noncoding RNAs in stem cells
por: McElhinney, James M.W.R., et al.
Publicado: (2020)

A Reciprocal Role of the Smad4‐Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells
por: Park, Jin Seok, et al.
Publicado: (2018)

p53‐TP53‐Induced Glycolysis Regulator Mediated Glycolytic Suppression Attenuates DNA Damage and Genomic Instability in Fanconi Anemia Hematopoietic Stem Cells
por: Li, Xue, et al.
Publicado: (2019)

Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte
por: Shi, Xiaojie, et al.
Publicado: (2019)

Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Osteogenic Differentiation by Modulating AMPK/ULK1‐Dependent Autophagy
por: Li, Zheng, et al.
Publicado: (2019)

Hes1 deficiency causes hematopoietic stem cell exhaustion
por: Ma, Zhilin, et al.
Publicado: (2020)

Genome‐wide CRISPR screen identifies ZIC2 as an essential gene that controls the cell fate of early mesodermal precursors to human heart progenitors
por: Xu, Jiejia, et al.
Publicado: (2020)

Bone Marrow Mesenchymal Stem Cells-Derived miR-21-5p Protects Grafted Islets Against Apoptosis by Targeting PDCD4
por: Wang, Jingwen, et al.
Publicado: (2022)

Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age
por: Turlo, Agnieszka J, et al.
Publicado: (2023)

Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis
por: Enomoto, Yasunori, et al.
Publicado: (2023)

Gfi-1B Promoter Remains Associated with Active Chromatin Marks Throughout Erythroid Differentiation of Human Primary Progenitor Cells
por: Laurent, Benoît, et al.
Publicado: (2009)

The efficacy and further functional advantages of random-base molecular barcodes for absolute and digital quantification of nucleic acid molecules
por: Ogawa, Taisaku, et al.
Publicado: (2017)

Data on the aquaporin gene expression differences among ρ(0), clinically relevant radioresistant, and the parental cells of human cervical cancer and human tongue squamous cell carcinoma
por: Takashi, Yuko, et al.
Publicado: (2018)

Data-independent proteome analysis of ARPE-19 cells
por: Koirala, Diwa, et al.
Publicado: (2018)

Enzymatic synthesis of geranyl acetate in packed bed reactor in supercritical carbon dioxide under various pressure-temperature conditions and reactor configurations
por: Bourkaib, Mohamed Chafik, et al.
Publicado: (2018)

Data on tumor progression of c-mos deficiency in murine models of Kras(G12D) lung and Apc(Min) colorectal cancer
por: Chen, Zhengxi, et al.
Publicado: (2018)

A proteomic dataset of secreted proteins by three Staphylococcus saprophyticus strains
por: Oliveira, Andrea Santana de, et al.
Publicado: (2018)

Peptidome profiling dataset of ovarian cancer and non-cancer proximal fluids: Ascites and blood sera
por: Shender, Victoria, et al.
Publicado: (2018)

Data on proteomic profiling of cells and extracellular vesicles of the melittin-resistant Acholeplasma laidlawii strain
por: Medvedeva, E.S., et al.
Publicado: (2019)

Dataset of the frequency patterns of publications annotated to human protein-coding genes, their protein products and genetic relevance
por: Zwick, Matthias, et al.
Publicado: (2019)

Dataset on fat body proteome of Anopheles stephensi Liston
por: Kumar, Manish, et al.
Publicado: (2019)

Mass spectrometry data from identification of host-defense related proteins using label-free quantitative proteomic analysis of milk whey from cows with Staphylococcus aureus subclinical mastitis
por: Abdelmegid, Shaimaa, et al.
Publicado: (2019)

Outlining the Grb2 interactome data and its interacting partners in HEK293 cells in absence and presence of epidermal growth factor
por: Duggal, Shweta, et al.
Publicado: (2019)

High-throughput mass spectrometry and bioinformatics analysis of breast cancer proteomic data
por: Gomig, Talita Helen Bombardelli, et al.
Publicado: (2019)

Protein profile of different cellular fractions from Mycobacterium tuberculosis strains after exposure to isoniazid
por: Nieto Ramirez, Luisa María, et al.
Publicado: (2019)

Human tear fluid proteome dataset for usage as a spectral library and for protein modeling
por: Guntermann, Annika, et al.
Publicado: (2019)

Spiked human substantia nigra proteome data set for use as a spectral library for protein modelling and protein mapping
por: Steinbach, Simone, et al.
Publicado: (2019)

Proteomic dataset of wolframin-deficient mouse heart and skeletal muscles
por: Eimre, Margus, et al.
Publicado: (2018)

A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion
por: Coleman, Orla, et al.
Publicado: (2018)

Data on proteomic profiling of extracellular vesicles of Acholeplasma laidlawii strains with increased resistance to antibiotics of different classes - ciprofloxacin and tetracycline
por: Mouzykantov, Alexey, et al.
Publicado: (2020)

Data set of the proteome of fresh and frozen thawed stallion spermatozoa
por: Martín-Cano, Francisco E., et al.
Publicado: (2020)

Proteomic datasets of uninfected and Staphylococcus aureus-infected goat milk
por: Pisanu, Salvatore, et al.
Publicado: (2020)

Data from differentially expressed proteins in platelet components associated with adverse transfusion reactions
por: Aloui, Chaker, et al.
Publicado: (2019)

Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages
por: Demircan, Turan, et al.
Publicado: (2020)

Shotgun proteomics datasets acquired on Gammarus pulex animals sampled from the wild
por: Gouveia, Duarte, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_uh333naki6avvtd86uhg8r4cgh