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Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature

Sclerosing microcystic adenocarcinoma (SMA) is a rare malignant tumor of the salivary glands that closely resembles cutaneous microcystic adnexal carcinoma (MAC). It was newly listed in the 5th edition of the WHO classification of head and neck tumors. This report describes the case of a 61-year-old...

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Autores principales: Fujii, Hiroyuki, Noguchi, Tadahide, Miura, Tamaki, Fujii, Nana, Isozaki, Takenori, Fujita, Akifumi, Niki, Toshiro, Matsuki, Mitsuru, Mori, Harushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427983/
https://www.ncbi.nlm.nih.gov/pubmed/37593335
http://dx.doi.org/10.1016/j.radcr.2023.07.050
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author Fujii, Hiroyuki
Noguchi, Tadahide
Miura, Tamaki
Fujii, Nana
Isozaki, Takenori
Fujita, Akifumi
Niki, Toshiro
Matsuki, Mitsuru
Mori, Harushi
author_facet Fujii, Hiroyuki
Noguchi, Tadahide
Miura, Tamaki
Fujii, Nana
Isozaki, Takenori
Fujita, Akifumi
Niki, Toshiro
Matsuki, Mitsuru
Mori, Harushi
author_sort Fujii, Hiroyuki
collection PubMed
description Sclerosing microcystic adenocarcinoma (SMA) is a rare malignant tumor of the salivary glands that closely resembles cutaneous microcystic adnexal carcinoma (MAC). It was newly listed in the 5th edition of the WHO classification of head and neck tumors. This report describes the case of a 61-year-old woman who presented with masses on the floor of the mouth. The masses showed low signal intensity on T2-weighted images (T2WI) and with low apparent diffusion coefficient (ADC) values. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) revealed a plateau or persistence after rapid initial enhancement. Histopathologically, the tumors comprised small infiltrating strands of cells that formed small ducts and cysts embedded in thick fibrous stroma, consistent with SMA. Low signal intensity on T2WI with a low ADC value and a plateau or persistence after rapid initial enhancement on DCE-MRI reflect the fibrous and cellular components of the tumor and can be considered characteristic MRI findings of SMA.
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spelling pubmed-104279832023-08-17 Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature Fujii, Hiroyuki Noguchi, Tadahide Miura, Tamaki Fujii, Nana Isozaki, Takenori Fujita, Akifumi Niki, Toshiro Matsuki, Mitsuru Mori, Harushi Radiol Case Rep Case Report Sclerosing microcystic adenocarcinoma (SMA) is a rare malignant tumor of the salivary glands that closely resembles cutaneous microcystic adnexal carcinoma (MAC). It was newly listed in the 5th edition of the WHO classification of head and neck tumors. This report describes the case of a 61-year-old woman who presented with masses on the floor of the mouth. The masses showed low signal intensity on T2-weighted images (T2WI) and with low apparent diffusion coefficient (ADC) values. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) revealed a plateau or persistence after rapid initial enhancement. Histopathologically, the tumors comprised small infiltrating strands of cells that formed small ducts and cysts embedded in thick fibrous stroma, consistent with SMA. Low signal intensity on T2WI with a low ADC value and a plateau or persistence after rapid initial enhancement on DCE-MRI reflect the fibrous and cellular components of the tumor and can be considered characteristic MRI findings of SMA. Elsevier 2023-08-03 /pmc/articles/PMC10427983/ /pubmed/37593335 http://dx.doi.org/10.1016/j.radcr.2023.07.050 Text en © 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fujii, Hiroyuki
Noguchi, Tadahide
Miura, Tamaki
Fujii, Nana
Isozaki, Takenori
Fujita, Akifumi
Niki, Toshiro
Matsuki, Mitsuru
Mori, Harushi
Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title_full Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title_fullStr Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title_full_unstemmed Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title_short Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature
title_sort magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427983/
https://www.ncbi.nlm.nih.gov/pubmed/37593335
http://dx.doi.org/10.1016/j.radcr.2023.07.050
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