Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome

BACKGROUND: Brugada syndrome (BrS) is a cardiac channelopathy that can result in sudden cardiac death (SCD). SCN5A is the most frequent gene linked to BrS, but the genotype–phenotype correlations are not completely matched. Clinical phenotypes of a particular SCN5A variant may range from asymptomati...

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Detalles Bibliográficos
Autores principales: Sun, Yaxun, Su, Jun, Wang, Xiaochen, Wang, Jue, Guo, Fengfeng, Qiu, Hangyuan, Fan, Hangping, Cai, Dongsheng, Wang, Hao, Lin, Miao, Wang, Wei, Feng, Ye, Fu, Guosheng, Gong, Tingyu, Liang, Ping, Jiang, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427992/
https://www.ncbi.nlm.nih.gov/pubmed/37544203
http://dx.doi.org/10.1016/j.ebiom.2023.104741

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