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The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP. YAP binds to TEADs and occupies the proximal promoter regions...
Autores principales: | Azzi, Abdelhalim, Tao, Zhipeng, Sun, Yang, Erb, Hannah, Guarino, Carla, Wu, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428131/ https://www.ncbi.nlm.nih.gov/pubmed/37593458 http://dx.doi.org/10.1016/j.isci.2023.107449 |
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