Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

[Image: see text] Theoretical concepts from polymer physics are often used to describe intrinsically disordered proteins (IDPs). However, amino acid interactions within and between regions of the protein can lead to deviations from typical polymer scaling behavior and even to short-lived secondary s...

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Detalles Bibliográficos
Autores principales: Heesink, Gobert, Marseille, Mirjam J., Fakhree, Mohammad A. A., Driver, Mark D., van Leijenhorst-Groener, Kirsten A., Onck, Patrick R., Blum, Christian, Claessens, Mireille M.A.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428166/
https://www.ncbi.nlm.nih.gov/pubmed/37407505
http://dx.doi.org/10.1021/acs.biomac.3c00404

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