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Tuning the Cross-Linking Density and Cross-Linker in Core Cross-Linked Polymeric Micelles and Its Effects on the Particle Stability in Human Blood Plasma and Mice

[Image: see text] Core cross-linked polymeric micelles (CCPMs) are designed to improve the therapeutic profile of hydrophobic drugs, reduce or completely avoid protein corona formation, and offer prolonged circulation times, a prerequisite for passive or active targeting. In this study, we tuned the...

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Detalles Bibliográficos
Autores principales: Bauer, Tobias A., Alberg, Irina, Zengerling, Lydia A., Besenius, Pol, Koynov, Kaloian, Slütter, Bram, Zentel, Rudolf, Que, Ivo, Zhang, Heyang, Barz, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428167/
https://www.ncbi.nlm.nih.gov/pubmed/37449781
http://dx.doi.org/10.1021/acs.biomac.3c00308