Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2

BACKGROUND: Endothelial glycocalyx (EG) is an active player and treatment target in inflammatory-related vascular leakage. The bone marrow mesenchymal stem cells (bMSCs) are promising potential treatments for leakage; however, the therapeutic effect and mechanism of bMSC on EG degradation needs to b...

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Detalles Bibliográficos
Autores principales: Li, Zhe, Xu, Yuqing, Lu, Shiyue, Gao, Yuan, Deng, Yuxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428537/
https://www.ncbi.nlm.nih.gov/pubmed/37587494
http://dx.doi.org/10.1186/s12964-023-01229-7

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