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Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesity

BACKGROUND: Microglia play a pivotal role in neuroinflammation, while obesity triggers hypothalamic microglia activation and inflammation. Sirt6 is an important regulator of energy metabolism in many peripheral tissues and hypothalamic anorexic neurons. However, the exact mechanism for microglia Sir...

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Detalles Bibliográficos
Autores principales:	Xiao, Xiaoxia, Hu, Huiling, Zhong, Yadi, Chen, Yingjian, Tang, Kaijia, Pan, Zhisen, Huang, Jiawen, Yang, Xiaoying, Wang, Qi, Gao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428617/ https://www.ncbi.nlm.nih.gov/pubmed/37582706 http://dx.doi.org/10.1186/s10020-023-00676-9

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