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P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS.
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429191/ http://dx.doi.org/10.1097/01.HS9.0000968764.90228.92 |
| _version_ | 1785090648998674432 |
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| author | Schalm, Stefanie Chutake, Yogesh Breitkopf, Susanne Mayo, Michele Dumont, Nancy Chen, Dapeng Dixit, Vaishali Karnik, Rahul Mcdonald, Alice Filiatrault, Jessica Proctor, William Qi, Frank Hu, Kan-Nian Weiss, Matt Gollerkeri, Ashwin Sharma, Kirti D Growney, Joseph Williams, Juliet |
| author_facet | Schalm, Stefanie Chutake, Yogesh Breitkopf, Susanne Mayo, Michele Dumont, Nancy Chen, Dapeng Dixit, Vaishali Karnik, Rahul Mcdonald, Alice Filiatrault, Jessica Proctor, William Qi, Frank Hu, Kan-Nian Weiss, Matt Gollerkeri, Ashwin Sharma, Kirti D Growney, Joseph Williams, Juliet |
| author_sort | Schalm, Stefanie |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-10429191 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Lippincott Williams & Wilkins |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-104291912023-08-17 P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. Schalm, Stefanie Chutake, Yogesh Breitkopf, Susanne Mayo, Michele Dumont, Nancy Chen, Dapeng Dixit, Vaishali Karnik, Rahul Mcdonald, Alice Filiatrault, Jessica Proctor, William Qi, Frank Hu, Kan-Nian Weiss, Matt Gollerkeri, Ashwin Sharma, Kirti D Growney, Joseph Williams, Juliet Hemasphere Posters Lippincott Williams & Wilkins 2023-08-08 /pmc/articles/PMC10429191/ http://dx.doi.org/10.1097/01.HS9.0000968764.90228.92 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access Abstract Book distributed under the Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) which allows third parties to download the articles and share them with others as long as they credit the author and the Abstract Book, but they cannot change the content in any way or use them commercially. |
| spellingShingle | Posters Schalm, Stefanie Chutake, Yogesh Breitkopf, Susanne Mayo, Michele Dumont, Nancy Chen, Dapeng Dixit, Vaishali Karnik, Rahul Mcdonald, Alice Filiatrault, Jessica Proctor, William Qi, Frank Hu, Kan-Nian Weiss, Matt Gollerkeri, Ashwin Sharma, Kirti D Growney, Joseph Williams, Juliet P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title | P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title_full | P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title_fullStr | P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title_full_unstemmed | P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title_short | P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. |
| title_sort | p464: pulse dosing of potent and selective heterobifunctional mdm2 degrader kt-253 drives tumor regression and demonstrates differentiated pharmacology compared to p53/mdm2 small molecule inhibitors. |
| topic | Posters |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429191/ http://dx.doi.org/10.1097/01.HS9.0000968764.90228.92 |
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