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P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS.
Autores principales: | Schalm, Stefanie, Chutake, Yogesh, Breitkopf, Susanne, Mayo, Michele, Dumont, Nancy, Chen, Dapeng, Dixit, Vaishali, Karnik, Rahul, Mcdonald, Alice, Filiatrault, Jessica, Proctor, William, Qi, Frank, Hu, Kan-Nian, Weiss, Matt, Gollerkeri, Ashwin, Sharma, Kirti, D Growney, Joseph, Williams, Juliet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429191/ http://dx.doi.org/10.1097/01.HS9.0000968764.90228.92 |
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