Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy

Osteoarthritis (OA) is the most common disabling joint disease with no effective disease modifying drugs. Extracellular vesicles released by several types of mesenchymal stem cells could promote cartilage repair and ameliorate OA pathology in animal models, representing a novel therapeutic strategy....

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Detalles Bibliográficos
Autores principales: Liu, Weixuan, Liu, Anqi, Li, Xujun, Sun, Ziyang, Sun, Zhenghua, Liu, Yaru, Wang, Gang, Huang, Dan, Xiong, Hao, Yu, Shiyang, Zhang, Xintao, Fan, Cunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429745/
https://www.ncbi.nlm.nih.gov/pubmed/37593145
http://dx.doi.org/10.1016/j.bioactmat.2023.06.012

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