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Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction

Selective prodrug activation at a tumor site is crucial to maximise the efficiency of chemotherapy approaches and minimise side effects due to off-site activation. In this paper, a new prodrug activation strategy is reported based on the bioorthogonal Staudinger reaction. The feasibility of this pro...

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Detalles Bibliográficos
Autores principales: Mitry, Madonna M. A., Boateng, Samuel Y., Greco, Francesca, Osborn, Helen M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429771/
https://www.ncbi.nlm.nih.gov/pubmed/37593579
http://dx.doi.org/10.1039/d3md00137g

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