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Protocol for establishing a coculture with fibroblasts and colorectal cancer organoids

The tumor microenvironment is essential for mediating drug resistance and tumor progression. Here, we present a coculture system, which enables drug testing of colorectal cancer organoids and fibroblasts without additional matrix components such as Matrigel or basement membrane extracts. First, we d...

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Detalles Bibliográficos
Autores principales:	Wallisch, Svenja, Neef, Sylvia Karin, Denzinger, Lukas, Mönch, Dina, Koch, Jana, Marzi, Julia, Mürdter, Thomas, Janssen, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430577/ https://www.ncbi.nlm.nih.gov/pubmed/37542715 http://dx.doi.org/10.1016/j.xpro.2023.102481

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