Cargando…

P787: ALTERNATIVE PATHWAY MASP-3 INHIBITOR OMS906: RESULTS FROM A FIRST-IN-MAN PHASE 1 STUDY IN HEALTHY SUBJECTS AND STUDY DESIGN OF TWO ONGOING CLINICAL TRIALS IN PATIENTS WITH PNH

Detalles Bibliográficos
Autores principales:	Griffin, Morag, Humphreys, Jane, Philpot, Edward, Jason Cummings, W., Pullman, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Posters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430637/ http://dx.doi.org/10.1097/01.HS9.0000970052.45858.28

Ejemplares similares

Characteristics of Taiwanese patients of PNH in the international PNH registry
por: Chou, Wen-Chien, et al.
Publicado: (2016)

Polymorphisms in the MASP1 Gene Are Associated with Serum Levels of MASP-1, MASP-3, and MAp44
por: Gytz Ammitzbøll, Christian, et al.
Publicado: (2013)

Mechanism Based Quality Control (MBQC) of Herbal Products: A Case Study YIV-906 (PHY906)
por: Lam, Wing, et al.
Publicado: (2018)

MAp19, the alternative splice product of the MASP2 gene
por: Degn, Søren E., et al.
Publicado: (2011)

787. Improving ED Sepsis Care
por: Sloan, William A, et al.
Publicado: (2019)

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1
por: Jenny, Lorenz, et al.
Publicado: (2015)

Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus
por: Xu, Wang‐Dong, et al.
Publicado: (2020)

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
por: Orsini, Franca, et al.
Publicado: (2016)

Association of MASP-2 Levels and MASP2 Gene Polymorphisms with Rheumatoid Arthritis in Patients and Their Relatives
por: Goeldner, Isabela, et al.
Publicado: (2014)

MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression
por: Maestri, Carlos Afonso, et al.
Publicado: (2018)

Risk factors for thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH): a nested case–control study in the International PNH Registry
por: Höchsmann, Britta, et al.
Publicado: (2023)

A complementary new drug for PNH
por: Brodsky, Robert A.
Publicado: (2020)

Management of paroxysmal nocturnal hemoglobinuria (PNH)
por: Luzzatto, Lucio
Publicado: (2022)

Mortality in 787,666 school pupils with and without autism: A cohort study
por: Smith, Gillian S, et al.
Publicado: (2020)

MASP-1 Increases Endothelial Permeability
por: Debreczeni, Márta L., et al.
Publicado: (2019)

The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
por: Kusakari, Kohei, et al.
Publicado: (2022)

Predictive Factors of Mortality in Population of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results from a Korean PNH Registry
por: Jang, Jun Ho, et al.
Publicado: (2016)

906 How Mandatory Public Reporting Undermines Infection Prevention: An Ethnographic Study
por: Szymczak, Julia E., et al.
Publicado: (2014)

Exome sequencing and analysis of 454,787 UK Biobank participants
por: Backman, Joshua D., et al.
Publicado: (2021)

Baseline clinical characteristics and disease burden in patients with paroxysmal nocturnal hemoglobinuria (PNH): updated analysis from the International PNH Registry
por: Schrezenmeier, Hubert, et al.
Publicado: (2020)

Leprosy Association with Low MASP-2 Levels Generated by MASP2 Haplotypes and Polymorphisms Flanking MAp19 Exon 5
por: Boldt, Angelica Beate Winter, et al.
Publicado: (2013)

S182: ORAL IPTACOPAN MONOTHERAPY INCREASES PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE VIA CONTROL OF INTRA- AND EXTRAVASCULAR HEMOLYSIS IN ANTI-C5-TREATED PNH PATIENTS WITH ANEMIA
por: Risitano, Antonio Maria, et al.
Publicado: (2023)

Development and characterization of narsoplimab, a selective MASP-2 inhibitor, for the treatment of lectin-pathway–mediated disorders
por: Dudler, Thomas, et al.
Publicado: (2023)

MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti‐MASP2 antibody narsoplimab
por: Elhadad, S., et al.
Publicado: (2020)

Autosplenectomy in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH)
por: Burns, Ethan, et al.
Publicado: (2019)

Pegcetacoplan: A New Opportunity for Complement Inhibition in PNH
por: Weitz, Ilene Ceil
Publicado: (2023)

MBL-associated serine proteases (MASPs) and infectious diseases
por: Beltrame, Marcia H., et al.
Publicado: (2015)

Unveiling the Great Therapeutic Potential of MASPs as Hemostatic Agents
por: Saad, Ashraf Abdullah
Publicado: (2022)

906. Surgical Site Infections in Children with Beta-Lactam Allergy: A Matched Cohort Study
por: Huang, Felicia Scaggs, et al.
Publicado: (2020)

Carpal Tunnel Syndrome: The Role of Occupational Factors Among 906 Workers
por: Ghasemi, Mohammad, et al.
Publicado: (2012)

伴PNH克隆的获得性再生障碍性贫血临床特征及PNH克隆演变分析
Publicado: (2016)

New Insights in Abdominal Pain in Paroxysmal Nocturnal Hemoglobinuria (PNH): A MRI Study
por: De Cobelli, Francesco, et al.
Publicado: (2015)

C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo
por: Ruseva, M M, et al.
Publicado: (2014)

Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)
por: Lobry, Camille, et al.
Publicado: (2019)

Fantasia in C minor, BWV906 Fifteen two-part inventions ; Fifteen three-part sinfonias (inventions) ; Chromatic fantasia and fugue : in D minor, BWV903 /
por: Bach, Johann Sebastian, 1685-1750
Publicado: (1994)

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked
por: Dobó, József, et al.
Publicado: (2016)

SUN-906 To Function or Not to Function: A Rare Case of Metachronous Hormone Syndrome
por: Amine, Adele, et al.
Publicado: (2020)

Herpes simplex encephalitis in adult patients with MASP-2 deficiency
por: Bibert, Stéphanie, et al.
Publicado: (2019)

run 787 - 26 GeV/c, Linear coupling effects on the effective height
por: Guignard, G
Publicado: (1977)

787 Two Year Follow Up of Microblading in Patients with a Facial Burn Injury
por: Brown, Melissa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p06icrurnei6po203kjihe64bc