Cargando…
Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli
BACKGROUND: Opioid receptors are naloxone-sensitive (MOP [mu: μ], DOP [delta: δ], and KOP [kappa: κ]) and naloxone-insensitive Nociceptin/Orphanin FQ (N/OFQ) peptide receptor (NOP). Clinically, most opioid analgesics target MOP. Angiogenesis is the formation of new blood vessels and involves endothe...
Autores principales: | Giakomidi, Despina, Khemiri, Sonja, Mahbuba, Wadhah, McVey, David G., Al-Janabi, Fatin, Guerrini, Remo, Calo, Girolamo, Ye, Shu, Lambert, David G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430811/ https://www.ncbi.nlm.nih.gov/pubmed/37588788 http://dx.doi.org/10.1016/j.bjao.2022.100110 |
Ejemplares similares
-
In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
por: Bird, Mark F., et al.
Publicado: (2022) -
Structure of the Nociceptin/Orphanin FQ Receptor in Complex with a Peptide Mimetic
por: Thompson, Aaron A., et al.
Publicado: (2012) -
Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands
por: Pacifico, Salvatore, et al.
Publicado: (2017) -
The Nociceptin/Orphanin FQ Receptor Antagonist UFP-101 Reduces Microvascular Inflammation to Lipopolysaccharide In Vivo
por: Brookes, Zoë L. S., et al.
Publicado: (2013) -
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist
por: Rizzi, Anna, et al.
Publicado: (2016)