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Effects of sevoflurane and its metabolite hexafluoroisopropanol on hypoxia/reoxygenation-induced injury and mitochondrial bioenergetics in murine cardiomyocytes

BACKGROUND: The volatile anaesthetic sevoflurane protects cardiac tissue from reoxygenation/reperfusion. Mitochondria play an essential role in conditioning. We aimed to investigate how sevoflurane and its primary metabolite hexafluoroisopropanol (HFIP) affect necrosis, apoptosis, and reactive oxyge...

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Detalles Bibliográficos
Autores principales:	Roth Z'graggen, Birgit, Urner, Martin, Beck-Schimmer, Beatrice, Schläpfer, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430838/ https://www.ncbi.nlm.nih.gov/pubmed/37587996 http://dx.doi.org/10.1016/j.bjao.2022.100116

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