Model‐based meta‐analysis of ethnic differences and their variabilities in clearance of oral drugs classified by clearance mechanism

In this study, the ethnic ratios (ERs) of oral clearance between Japanese and Western populations were subjected to model‐based meta‐analysis (MBMA) for 81 drugs evaluated in 673 clinical studies. The drugs were classified into eight groups according to the clearance mechanism, and the ER for each g...

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Detalles Bibliográficos
Autores principales: Sato, Hiromi, Marutani, Rika, Takaoka, Ryota, Mori‐Fegan, Daniel, Wang, Xinying, Maeda, Kazuya, Kusuhara, Hiroyuki, Suzuki, Hiroshi, Yoshioka, Hideki, Hisaka, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431045/
https://www.ncbi.nlm.nih.gov/pubmed/37309079
http://dx.doi.org/10.1002/psp4.12980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431045/
https://www.ncbi.nlm.nih.gov/pubmed/37309079
http://dx.doi.org/10.1002/psp4.12980

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