The IL-10 receptor inhibits cell extrinsic signals necessary for STAT1-dependent macrophage accumulation during colitis

The loss of IL-10R function leads to severe early onset colitis and, in murine models, is associated with the accumulation of immature inflammatory colonic macrophages. We have shown that IL-10R-deficient colonic macrophages exhibit increased STAT1-dependent gene expression, suggesting that IL-10R-m...

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Detalles Bibliográficos
Autores principales: Patik, Izabel, Redhu, Naresh S., Eran, Alal, Bao, Bin, Nandy, Anubhab, Tang, Ying, El Sayed, Shorouk, Shen, Zeli, Glickman, Jonathan, Fox, James G., Snapper, Scott B., Horwitz, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431098/
https://www.ncbi.nlm.nih.gov/pubmed/36868479
http://dx.doi.org/10.1016/j.mucimm.2023.02.006

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