Cargando…

Reelin Rescues Behavioral, Electrophysiological, and Molecular Metrics of a Chronic Stress Phenotype in a Similar Manner to Ketamine

Over the past decade, ketamine, an NMDA receptor antagonist, has demonstrated fast-acting antidepressant effects previously unseen with monoaminergic-based therapeutics. Concerns regarding psychotomimetic effects limit the use of ketamine for certain patient populations. Reelin, an extracellular mat...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnston, Jenessa N., Allen, Josh, Shkolnikov, Irene, Sanchez-Lafuente, Carla L., Reive, Brady S., Scheil, Kaylene, Liang, Stanley, Christie, Brian R., Kalynchuk, Lisa E., Caruncho, Hector J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431216/
https://www.ncbi.nlm.nih.gov/pubmed/37550058
http://dx.doi.org/10.1523/ENEURO.0106-23.2023