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B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway

BACKGROUND: Cancer stem-like cells (CSCs) are a small subset of cells in tumors that exhibit self-renewal and differentiation properties. CSCs play a vital role in tumor formation, progression, relapse, and therapeutic resistance. B7-H3, an immunoregulatory protein, has many protumor functions. Howe...

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Detalles Bibliográficos
Autores principales: Xia, Lu, Chen, Yuqi, Li, Juntao, Wang, Jiayu, Shen, Kanger, Zhao, Anjing, Jin, Haiyan, Zhang, Guangbo, Xi, Qinhua, Xia, Suhua, Shi, Tongguo, Li, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431251/
https://www.ncbi.nlm.nih.gov/pubmed/37488673
http://dx.doi.org/10.1097/CM9.0000000000002772