Cargando…

B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway

BACKGROUND: Cancer stem-like cells (CSCs) are a small subset of cells in tumors that exhibit self-renewal and differentiation properties. CSCs play a vital role in tumor formation, progression, relapse, and therapeutic resistance. B7-H3, an immunoregulatory protein, has many protumor functions. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Lu, Chen, Yuqi, Li, Juntao, Wang, Jiayu, Shen, Kanger, Zhao, Anjing, Jin, Haiyan, Zhang, Guangbo, Xi, Qinhua, Xia, Suhua, Shi, Tongguo, Li, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431251/ https://www.ncbi.nlm.nih.gov/pubmed/37488673 http://dx.doi.org/10.1097/CM9.0000000000002772

Ejemplares similares

Increased expression of pAKT is associated with radiation resistance in cervical cancer
por: Kim, T-J, et al.
Publicado: (2006)

HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification
por: Wang, Jiayu, et al.
Publicado: (2023)

B7H3 increases ferroptosis resistance by inhibiting cholesterol metabolism in colorectal cancer
por: Jin, Haiyan, et al.
Publicado: (2023)

Expression of the Androgen Receptor, pAkt, and pPTEN in Breast Cancer and Their Potential in Prognostication()
por: Sultana, Aisha, et al.
Publicado: (2014)

Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT
por: Aboouf, Mostafa A., et al.
Publicado: (2022)

B7-H3 suppresses doxorubicin-induced senescence-like growth arrest in colorectal cancer through the AKT/TM4SF1/SIRT1 pathway
por: Wang, Ruoqin, et al.
Publicado: (2021)

Identification of pAKT as a pharmacodynamic marker for MER kinase in human melanoma G361 cells
por: Chen, Yaoyu, et al.
Publicado: (2020)

pERK/pAkt phenotyping in circulating tumor cells as a biomarker for sorafenib efficacy in patients with advanced hepatocellular carcinoma
por: Li, Jun, et al.
Publicado: (2015)

Yanghe Huayan decoction inhibits the capability of trans-endothelium and angiogenesis of HER2+ breast cancer via pAkt signaling
por: Liu, Xiao-Fei, et al.
Publicado: (2019)

Expression of pAkt is associated with a poor prognosis in Chinese women with invasive ductal breast cancer
por: Zhou, Ling, et al.
Publicado: (2018)

Modulation of signaling cross-talk between pJNK and pAKT generates optimal apoptotic response
por: Biswas, Sharmila, et al.
Publicado: (2022)

Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma
por: Xie, Xiaoxue, et al.
Publicado: (2013)

Ras Isoprenylation and pAkt Inhibition by Zoledronic Acid and Fluvastatin Enhances Paclitaxel Activity in T24 Bladder Cancer Cells
por: Li, Shaojuan, et al.
Publicado: (2011)

Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway
por: Daya, Minerva, et al.
Publicado: (2018)

Circular RNA circLDLR facilitates cancer progression by altering the miR-30a-3p/SOAT1 axis in colorectal cancer
por: Wang, Ruoqin, et al.
Publicado: (2022)

Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis
por: Jana, Sayantan, et al.
Publicado: (2016)

Pathobiological Implications of the Expression of EGFR, pAkt, NF-κB and MIC-1 in Prostate Cancer Stem Cells and Their Progenies
por: Mimeault, Murielle, et al.
Publicado: (2012)

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival
por: Schultz, Chad R, et al.
Publicado: (2012)

Calpain-2 Enhances Non-Small Cell Lung Cancer Progression and Chemoresistance to Paclitaxel via EGFR-pAKT Pathway
por: Xu, Fengkai, et al.
Publicado: (2019)

Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats
por: Gan, Li, et al.
Publicado: (2021)

B7-H5 blockade enhances CD8(+) T-cell-mediated antitumor immunity in colorectal cancer
por: Wang, Jiayu, et al.
Publicado: (2021)

CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways
por: Nuvoli, Barbara, et al.
Publicado: (2014)

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways
por: Rai, Sachchida N., et al.
Publicado: (2017)

Imatinib Mesylate Reduces Neurotrophic Factors and pERK and pAKT Expression in Urinary Bladder of Female Mice With Cyclophosphamide-Induced Cystitis
por: Perkins, Megan, et al.
Publicado: (2022)

Loss of Bmp2 impairs odontogenesis via dysregulating pAkt/pErk/GCN5/Dlx3/Sp7
por: Chen, Shuo, et al.
Publicado: (2023)

Correction: Yanghe Huayan Decoction inhibit the capability of trans-endothelium and angiogenesis of HER2+ breast cancer via pAkt signaling
Publicado: (2023)

The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
por: Peterson, Stephen J., et al.
Publicado: (2009)

Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung
por: Stjernström, Annika, et al.
Publicado: (2014)

Detection of pAkt protein in imprint cytology of invasive breast cancer: Correlation with HER2/neu, hormone receptors, and other clinicopathological variables
por: Vasou, Olympia, et al.
Publicado: (2015)

Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling
por: Chen, Xuan, et al.
Publicado: (2020)

Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens' Minisatellite 33.15-Tagged Transcript pAKT-45 Variants
por: Shahbaaz, Mohd, et al.
Publicado: (2020)

Correction: CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways
por: Nuvoli, Barbara, et al.
Publicado: (2022)

Expression Levels of GHRH-Receptor, pAkt and Hsp90 Predict 10-Year Overall Survival in Patients with Locally Advanced Rectal Cancer
por: Fodor, Dávid, et al.
Publicado: (2023)

Dual regulation of Akt and glutathione caused by isoalantolactone effectively triggers human ovarian cancer cell apoptosis: Dual regulations of Akt and glutathione
por: Xie, Zhoufan, et al.
Publicado: (2023)

Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes
por: Hewage, Susara Ruwan Kumara Madduma, et al.
Publicado: (2017)

Sensitization of Cancer Cells through Reduction of Total Akt and Downregulation of Salinomycin-Induced pAkt, pGSk3β, pTSC2, and p4EBP1 by Cotreatment with MK-2206
por: Choi, Ae-Ran, et al.
Publicado: (2014)

Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
por: Harlé, A, et al.
Publicado: (2015)

Clinical significance of pAkt and pErk1/2 expression in early-stage breast cancer patients treated with anthracycline-based adjuvant chemotherapy
por: LIU, WENJUAN, et al.
Publicado: (2015)

K‐Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines
por: Yeung, Yvonne, et al.
Publicado: (2017)

Dietary alpha‐ketoglutarate inhibits SARS CoV‐2 infection and rescues inflamed lungs to restore O(2) saturation by inhibiting pAkt
por: Agarwal, Sakshi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_25su65l3t4jdc0l0aiklcalq2e